1.ApplicationNumber: US-58197045-A
1.PublishNumber: US-2437561-A
2.Date Publish: 19480309
3.Inventor: SCHAAF FRITZ

4.Inventor Harmonized: FRITZ SCHAAF()

5.Country: US
6.Claims:

7.Description:
(en)Patented Mar. 9, 1948 2,437,561 PREPARATION FOR THE CARE on THE SKIN Fritz Schaaf, Basel, Switzerland, assiguor to Ciba Pharmaceutical Products 1110., Summit, N. J a corporation of New Jersey No Drawing. Application March 9, 1945, Serial No. 581,970. In Switzerland January 3, 1944 Section 1, Public Law 690, August 8, 1946 Patent expires January 3, 1964 2 Claims. 1
The care of the skin by means of cosmetics follows the aim of preserving the skin in its normal condition. Numerous preparations are known which are intended to serve this purpose. Those which contain substances having a vitamin F action are considered to be particularly suitable, a fact which has also been demonstrated experimentally [F. Grandel, Fette und Seifen, 46, 151, (1939)]. Such preparations are generally used in the form of liquid or semi-liquid emulsions. The specific component is generally mainly dissolved in the fatty phase.
It has now been found that a particularly satisfactory preparation for the care of the skin can be obtained by adding substances with a vitamin F effect plus nicotinamide to the usual preparations. In this way a definite efiect .can be produced with considerably smaller quantities of the substances having a vitamin F effect, than if these substances are used without nicotinamide. The simultaneous addition of emulsifying agents also proved to be advantageous.
Amongst the substances possessing a vitamin F eiTect may be mentioned: multi-unsaturated fatty acids and their esters or natural products containing same, e. g., linoleic acid, its esters, sunflower oil, nut oil, poppy oil, etc.
The preparations for the care of the skin can be used in the form of creamy or liquid emulsions.
Example 1 Parts by weight Stearic a 22.0 Sunflower oil 5.0 Anhydrous wool-fat 2.2 Purified cetyl alcohol 0.6
p-Hydroxybenzoic-acid-methyl-ester l 0.2
are melted on a water-bath at 90 C. until a clear mass is obtained and then emulsified with a mixture at the same temperature consisting of Parts by weight Glycerine- 8.0 A 0.1 percent. nicotinamide solution in After stirring until cold, 0.5 part by weight of an aromatic mixture is added. 7
In this way a preparation for the care of the skin, which can be used in the form of a facecream, is obtained.
In the above example 2.5 parts by weight of linoleic acid could be used instead of 5.0 parts by weight of sunflower-oil.
Example 2 are added to this solution, the whole heated on a water-bath until homogeneously mixed, then stirred until the temperature has fallen to 45 0.. and 0.3 part by weight of aromatic mixture added.
A solution containing Parts by weight A sodium salt of a sulfonic acid which is derived from a i-substituted benzimidazole alkylated at the nitrogen atom and whose substituent contains 9 to 16 carbon atcms A 0.1 percent. nicotinamide solution in water 18.0 Distilled water 49.7
which had been warmed to 45 C. is added in small portions. shaking continually, and emulsified until the mixture has reached room temperature. In this way a preparation for the care of the skin, which can be used in the form of a "face-milk is obtained.
What I claim is:
1. A cosmetic preparation for the care of the skin containing sunflower 011 plus nicotinamide.
2. A cosmetic preparation for the care of the skin containing a member selected from the group consisting of the naturally-occurring multi-unsaturated fatty acids and their naturally- Grandel, A. P. C. Publication Ser. No. 275,543, occurring esters, plus nicotinamide. pub. May 11, 1943 (167-81 box 14).
FRITZ SCHAAF. Journal of the American Medical Association, Jan. 27, 1945, page 246 (167-81 box 14). (Copy REFERENCES CITED 5 in Sci Lib) The following references are of record in the De Navarre, Chemistry and Manufacture of file of this patent: Cosmetics (1941), pages 656, 657. (Copy in Div.
UNITED STATES PATENT Eller et al., Journal of the American Medical Number Name Date Association, vol. 114, page 2003, May 18, 1940,
2,036,525 Granacher Apr. 7, 1936 167-81 box 14. (Copyin Sci. Lib.)
. i U,-;S; Dispensatory, 23d ed. (1943), page 1391. OTHER REFERENCES (gqpy in Goodman, Cosmetic Dermatology (1936), 1 554,560, I
Certificate of Correction Patent N 0. 2,437,561. March 9, 1948. FRITZ SOHAAF It is hereby certified that errors appear in the printed specification of the above numbered patent requiring correction as follows: Column 2, line 18, Example 2, after warm in insert the words and period 5 parts by weight of paraflin 011.; line 20, strike out Paraflin oil 5; and that the said Letters Patent should be read with these corrections therein that the same may conform to the record of the case in the Patent Ofiice.
Signed and sealed this 18th day of May, A. D. 1948.
THOMAS E MURPHY,
Assistant Uonuniasioner of Patents.